2. Induced Disease Models Products Immunology/Inflammation
  3. Immunology and Inflammatory Disease Models MHC
  4. Hapten
  5. DB28

DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands.

For research use only. We do not sell to patients.

DB28 Chemical Structure

DB28 Chemical Structure

CAS No. : 16296-42-7

Size Price Stock Quantity
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

DB28 Related Antibodies

Top Publications Citing Use of Products

View All MHC Isoform Specific Products:

View All Isoforms
MHC I

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands[1].

Molecular Weight

227.17

Formula

C8H9N3O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCNC(C(NC1=O)=CC(N1)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (440.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4020 mL 22.0099 mL 44.0199 mL
5 mM 0.8804 mL 4.4020 mL 8.8040 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4020 mL 22.0099 mL 44.0199 mL 110.0497 mL
5 mM 0.8804 mL 4.4020 mL 8.8040 mL 22.0099 mL
10 mM 0.4402 mL 2.2010 mL 4.4020 mL 11.0050 mL
15 mM 0.2935 mL 1.4673 mL 2.9347 mL 7.3366 mL
20 mM 0.2201 mL 1.1005 mL 2.2010 mL 5.5025 mL
25 mM 0.1761 mL 0.8804 mL 1.7608 mL 4.4020 mL
30 mM 0.1467 mL 0.7337 mL 1.4673 mL 3.6683 mL
40 mM 0.1100 mL 0.5502 mL 1.1005 mL 2.7512 mL
50 mM 0.0880 mL 0.4402 mL 0.8804 mL 2.2010 mL
60 mM 0.0734 mL 0.3668 mL 0.7337 mL 1.8342 mL
80 mM 0.0550 mL 0.2751 mL 0.5502 mL 1.3756 mL
100 mM 0.0440 mL 0.2201 mL 0.4402 mL 1.1005 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

DB28 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DB2816296-42-7DB 28DB-28MHCMajor Histocompatibility ComplexMAITMR1MR1Tantigenligandmucosal-associated invariant T cellInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
DB28
Cat. No.:
HY-W168754
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.