2. GPCR/G Protein
  3. GLP Receptor
  4. DD202-114

DD202-114 is a potent and selective GLP1R agonist. DD202-114 promots cAMP accumulation. DD202-114 reduces blood glucose levels and food intake. DD202-114 has the potential for the research of type 2 diabetes (T2DM) and obesity.

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DD202-114 Chemical Structure

DD202-114 Chemical Structure

CAS No. : 2886728-09-0

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5 mg USD 170 In-stock
10 mg USD 275 In-stock
25 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

DD202-114 Related Antibodies

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Description

DD202-114 is a potent and selective GLP1R agonist. DD202-114 promots cAMP accumulation. DD202-114 reduces blood glucose levels and food intake. DD202-114 has the potential for the research of type 2 diabetes (T2DM) and obesity[1].

IC50 & Target

GLP1R[1]
Molecular Weight

586.65

Formula

C33H35FN4O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C2C(N(C(CN3CCC(C4=NC(OCC5=C(C=C(C=C5)C6COC6)F)=CC=C4)CC3)=N2)C[C@@H]7CCO7)=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (213.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7046 mL 8.5230 mL 17.0459 mL
5 mM 0.3409 mL 1.7046 mL 3.4092 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7046 mL 8.5230 mL 17.0459 mL 42.6148 mL
5 mM 0.3409 mL 1.7046 mL 3.4092 mL 8.5230 mL
10 mM 0.1705 mL 0.8523 mL 1.7046 mL 4.2615 mL
15 mM 0.1136 mL 0.5682 mL 1.1364 mL 2.8410 mL
20 mM 0.0852 mL 0.4261 mL 0.8523 mL 2.1307 mL
25 mM 0.0682 mL 0.3409 mL 0.6818 mL 1.7046 mL
30 mM 0.0568 mL 0.2841 mL 0.5682 mL 1.4205 mL
40 mM 0.0426 mL 0.2131 mL 0.4261 mL 1.0654 mL
50 mM 0.0341 mL 0.1705 mL 0.3409 mL 0.8523 mL
60 mM 0.0284 mL 0.1420 mL 0.2841 mL 0.7102 mL
80 mM 0.0213 mL 0.1065 mL 0.2131 mL 0.5327 mL
100 mM 0.0170 mL 0.0852 mL 0.1705 mL 0.4261 mL
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DD202-114 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DD202-1142886728-09-0GLP Receptortype 2 diabetes (T2DM)obesitycAMPblood glucosefood intakeInhibitorinhibitorinhibit

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