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  4. Deaminase inhibitor-1

Deaminase inhibitor-1 is a small molecule inhibitor of APOBEC3G DNA Deaminase, with an IC50 value of 18.9 μM.

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Deaminase inhibitor-1 Chemical Structure

Deaminase inhibitor-1 Chemical Structure

CAS No. : 397878-17-0

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10 mg USD 70 In-stock
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Description

Deaminase inhibitor-1 is a small molecule inhibitor of APOBEC3G DNA Deaminase, with an IC50 value of 18.9 μM[1].

Molecular Weight

314.20

Formula

C11H12BrN3OS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C1NN=C(CC2=CC=C(OC)C(Br)=C2)N1C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (397.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1827 mL 15.9134 mL 31.8269 mL
5 mM 0.6365 mL 3.1827 mL 6.3654 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1827 mL 15.9134 mL 31.8269 mL 79.5672 mL
5 mM 0.6365 mL 3.1827 mL 6.3654 mL 15.9134 mL
10 mM 0.3183 mL 1.5913 mL 3.1827 mL 7.9567 mL
15 mM 0.2122 mL 1.0609 mL 2.1218 mL 5.3045 mL
20 mM 0.1591 mL 0.7957 mL 1.5913 mL 3.9784 mL
25 mM 0.1273 mL 0.6365 mL 1.2731 mL 3.1827 mL
30 mM 0.1061 mL 0.5304 mL 1.0609 mL 2.6522 mL
40 mM 0.0796 mL 0.3978 mL 0.7957 mL 1.9892 mL
50 mM 0.0637 mL 0.3183 mL 0.6365 mL 1.5913 mL
60 mM 0.0530 mL 0.2652 mL 0.5304 mL 1.3261 mL
80 mM 0.0398 mL 0.1989 mL 0.3978 mL 0.9946 mL
100 mM 0.0318 mL 0.1591 mL 0.3183 mL 0.7957 mL
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Deaminase inhibitor-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deaminase inhibitor-1397878-17-0Deaminase inhibitor1Deaminase inhibitor 1HIVHuman immunodeficiency virusAPOBEC3GMycobacteriumtuberculosis shikimate kinaseInhibitorinhibitorinhibit

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