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  4. Dehydro-ZINC39395747

Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells.

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Dehydro-ZINC39395747 Chemical Structure

Dehydro-ZINC39395747 Chemical Structure

CAS No. : 433248-87-4

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1 mg USD 160 In-stock
5 mg USD 400 In-stock
10 mg USD 680 In-stock
50 mg USD 1900 In-stock
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Description

Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].

Molecular Weight

291.35

Formula

C12H9N3O2S2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C=C(CSC1=NC2=CC=CC=C2O1)N3)NC3=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (34.32 mM; ultrasonic and adjust pH to 6 with HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4323 mL 17.1615 mL 34.3230 mL
5 mM 0.6865 mL 3.4323 mL 6.8646 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4323 mL 17.1615 mL 34.3230 mL 85.8074 mL
5 mM 0.6865 mL 3.4323 mL 6.8646 mL 17.1615 mL
10 mM 0.3432 mL 1.7161 mL 3.4323 mL 8.5807 mL
15 mM 0.2288 mL 1.1441 mL 2.2882 mL 5.7205 mL
20 mM 0.1716 mL 0.8581 mL 1.7161 mL 4.2904 mL
25 mM 0.1373 mL 0.6865 mL 1.3729 mL 3.4323 mL
30 mM 0.1144 mL 0.5720 mL 1.1441 mL 2.8602 mL
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Dehydro-ZINC39395747 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dehydro-ZINC39395747433248-87-4OthersCYB5R3NObioavailabilityhypertensionderivativeZINC39395747Inhibitorinhibitorinhibit

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