Deltorphin 2 TFA (Synonyms: [D-Ala2]-Deltorphin II TFA)

Name: Deltorphin 2 TFA
Brand: MedChemExpress
SKU: HY-P1013A
Rating: 5.0 (2 reviews)

Cat. No.: HY-P1013A Purity: 99.88%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Deltorphin 2 TFA is a selective peptide agonist for the δ opioid receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Deltorphin 2 TFA Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 216	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 396	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 792	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Deltorphin 2 TFA:

Deltorphin 2 In-stock

2 Publications Citing Use of MCE Deltorphin 2 TFA

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View All Isoforms

μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

Biological Activity
Purity & Documentation
References
Customer Review

Description

Deltorphin 2 TFA is a selective peptide agonist for the δ opioid receptor^[1].

IC₅₀ & Target

δ Opioid Receptor/DOR

In Vitro

Deltorphin 2 ([D-Ala2]-Deltorphin II) is enzymatically stable, amphibian heptapeptides that has a high affinity and selectivity for delta-opioid receptor. Deltorphin 2 is the most selective natural delta opioid receptor agonist^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

896.91

Formula

C₄₀H₅₅F₃N₈O₁₂

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (55.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : ≥ 50 mg/mL (55.75 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1149 mL	5.5747 mL	11.1494 mL
5 mM	0.2230 mL	1.1149 mL	2.2299 mL
10 mM	0.1115 mL	0.5575 mL	1.1149 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (2.79 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (2.79 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (2.79 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (247 KB) LCMS (91 KB) Elemental Analysis Report (106 KB)

Handling Instructions (2659 KB)

References

[1]. Thomas SA, et al. Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J Pharmacol Exp Ther. 1997 May;281(2):817-25. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	1.1149 mL	5.5747 mL	11.1494 mL	27.8735 mL
	5 mM	0.2230 mL	1.1149 mL	2.2299 mL	5.5747 mL
	10 mM	0.1115 mL	0.5575 mL	1.1149 mL	2.7873 mL
	15 mM	0.0743 mL	0.3716 mL	0.7433 mL	1.8582 mL
	20 mM	0.0557 mL	0.2787 mL	0.5575 mL	1.3937 mL
	25 mM	0.0446 mL	0.2230 mL	0.4460 mL	1.1149 mL
	30 mM	0.0372 mL	0.1858 mL	0.3716 mL	0.9291 mL
	40 mM	0.0279 mL	0.1394 mL	0.2787 mL	0.6968 mL
	50 mM	0.0223 mL	0.1115 mL	0.2230 mL	0.5575 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Deltorphin 2 TFA Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deltorphin 2[D-Ala2]-Deltorphin IIDeltorphin2Deltorphin-2Opioid ReceptorInhibitorinhibitorinhibit

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Deltorphin 2 TFA (Synonyms: [D-Ala2]-Deltorphin II TFA)

Customer Review

Other Forms of Deltorphin 2 TFA:

Deltorphin 2 TFA Related Antibodies

2 Publications Citing Use of MCE Deltorphin 2 TFA

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All Opioid Receptor Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

Deltorphin 2 TFA Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Deltorphin 2 TFA Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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