2. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  3. Insulin Receptor Akt
  4. Demethylasterriquinone B1

Demethylasterriquinone B1  (Synonyms: DAQ B1; L-783281; Dimethylasterriquinone)

Cat. No.: HY-107586 Purity: 98.10%
COA Handling Instructions

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Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT.

For research use only. We do not sell to patients.

Demethylasterriquinone B1 Chemical Structure

Demethylasterriquinone B1 Chemical Structure

CAS No. : 78860-34-1

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1 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

Demethylasterriquinone B1 Related Antibodies

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Description

Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT[1].

Molecular Weight

506.59

Formula

C32H30N2O4
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

C=CC(C)(C1=C(C(C(C(O)=C2C3=CNC4=C3C=CC=C4C/C=C(C)/C)=O)=C(O)C2=O)C5=C(C=CC=C5)N1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMF : 15 mg/mL (29.61 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9740 mL 9.8699 mL 19.7398 mL
5 mM 0.3948 mL 1.9740 mL 3.9480 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.10%

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 1.9740 mL 9.8699 mL 19.7398 mL 49.3496 mL
5 mM 0.3948 mL 1.9740 mL 3.9480 mL 9.8699 mL
10 mM 0.1974 mL 0.9870 mL 1.9740 mL 4.9350 mL
15 mM 0.1316 mL 0.6580 mL 1.3160 mL 3.2900 mL
20 mM 0.0987 mL 0.4935 mL 0.9870 mL 2.4675 mL
25 mM 0.0790 mL 0.3948 mL 0.7896 mL 1.9740 mL
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Demethylasterriquinone B1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Demethylasterriquinone B178860-34-1DAQ B1 L-783281 DimethylasterriquinoneDemethylasterriquinone B 1Demethylasterriquinone B-1DAQ B 1DAQ B-1L783281L 783281L-783281Insulin ReceptorAktPKBProtein kinase BInsulin receptorIR β subunitPIK3AKTInhibitorinhibitorinhibit

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