2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Dephospho-CoA

Dephospho-CoA is A direct precursor of Coenzyme A (CoA). Dephospho-CoA kinase (DPCK) catalyzes the ATP-dependent phosphorylation of Dephospho-CoA, the final step in coenzyme A (CoA) biosynthesis.

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Dephospho-CoA Chemical Structure

Dephospho-CoA Chemical Structure

CAS No. : 3633-59-8

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Based on 1 publication(s) in Google Scholar

Dephospho-CoA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Dephospho-CoA

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Description

Dephospho-CoA is A direct precursor of Coenzyme A (CoA). Dephospho-CoA kinase (DPCK) catalyzes the ATP-dependent phosphorylation of Dephospho-CoA, the final step in coenzyme A (CoA) biosynthesis[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

687.55

Formula

C21H35N7O13P2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (72.72 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4544 mL 7.2722 mL 14.5444 mL
5 mM 0.2909 mL 1.4544 mL 2.9089 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥96.0%

SDS (251 KB)

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4544 mL 7.2722 mL 14.5444 mL 36.3610 mL
5 mM 0.2909 mL 1.4544 mL 2.9089 mL 7.2722 mL
10 mM 0.1454 mL 0.7272 mL 1.4544 mL 3.6361 mL
15 mM 0.0970 mL 0.4848 mL 0.9696 mL 2.4241 mL
20 mM 0.0727 mL 0.3636 mL 0.7272 mL 1.8180 mL
25 mM 0.0582 mL 0.2909 mL 0.5818 mL 1.4544 mL
30 mM 0.0485 mL 0.2424 mL 0.4848 mL 1.2120 mL
40 mM 0.0364 mL 0.1818 mL 0.3636 mL 0.9090 mL
50 mM 0.0291 mL 0.1454 mL 0.2909 mL 0.7272 mL
60 mM 0.0242 mL 0.1212 mL 0.2424 mL 0.6060 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dephospho-CoA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dephospho-CoA3633-59-8Endogenous MetaboliteInhibitorinhibitorinhibit

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