2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. Desethoxy Quetiapine dihydrochloride

Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine (HY-12723)-induced climbing and swimming disruption in mouse models.

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Desethoxy Quetiapine dihydrochloride Chemical Structure

Desethoxy Quetiapine dihydrochloride Chemical Structure

CAS No. : 329218-14-6

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Desethoxy Quetiapine dihydrochloride Related Antibodies

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Description

Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine (HY-12723)-induced climbing and swimming disruption in mouse models[1].

IC50 & Target

D2 Receptor

1330 nM (IC50)

Molecular Weight

412.38

Formula

C19H23Cl2N3OS
CAS No.
SMILES

OCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=CC=CC=C42.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Desethoxy Quetiapine dihydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desethoxy Quetiapine329218-14-6Dopamine ReceptormouseantipsychoticdyskineticInhibitorinhibitorinhibit

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