Diclofenac methyl ester

Cat. No.: HY-114689 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Diclofenac methyl ester is a diclofenac (HY-15036) derivative, which exhibits acute cytotoxicity with a LC₅₀ of 0.5 mg/L in H. azteca.

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Diclofenac methyl ester Chemical Structure

CAS No. : 15307-78-5

Size	Price	Stock	Quantity
5 mg	USD 29	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 45	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Purity & Documentation
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Description

Diclofenac methyl ester is a diclofenac (HY-15036) derivative, which exhibits acute cytotoxicity with a LC₅₀ of 0.5 mg/L in H. azteca^[1].

Molecular Weight

310.18

Formula

C₁₅H₁₃Cl₂NO₂

CAS No.

15307-78-5

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL (40.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2239 mL	16.1197 mL	32.2393 mL
5 mM	0.6448 mL	3.2239 mL	6.4479 mL
10 mM	0.3224 mL	1.6120 mL	3.2239 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Fu Q, et al., Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms. Environ Sci Technol. 2020 Apr 7;54(7):4400-4408. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.2239 mL	16.1197 mL	32.2393 mL	80.5984 mL
	5 mM	0.6448 mL	3.2239 mL	6.4479 mL	16.1197 mL
	10 mM	0.3224 mL	1.6120 mL	3.2239 mL	8.0598 mL
	15 mM	0.2149 mL	1.0746 mL	2.1493 mL	5.3732 mL
	20 mM	0.1612 mL	0.8060 mL	1.6120 mL	4.0299 mL
	25 mM	0.1290 mL	0.6448 mL	1.2896 mL	3.2239 mL
	30 mM	0.1075 mL	0.5373 mL	1.0746 mL	2.6866 mL
	40 mM	0.0806 mL	0.4030 mL	0.8060 mL	2.0150 mL