2. Immunology/Inflammation Apoptosis
  3. COX Apoptosis
  4. Diclofenac (Sodium) (Standard)

Diclofenac (Sodium) (Standard)  (Synonyms: GP 45840 (Standard))

Cat. No.: HY-15037R Purity: ≥98%
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Diclofenac (Sodium) (Standard) is the analytical standard of Diclofenac (Sodium). This product is intended for research and analytical applications. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

For research use only. We do not sell to patients.

Diclofenac (Sodium) (Standard) Chemical Structure

Diclofenac (Sodium) (Standard) Chemical Structure

CAS No. : 15307-79-6

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Description

Diclofenac (Sodium) (Standard) is the analytical standard of Diclofenac (Sodium). This product is intended for research and analytical applications. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Molecular Weight

318.13

Formula

C14H10Cl2NNaO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Diclofenac (Sodium) (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diclofenac (Sodium) (Standard)15307-79-6GP 45840 (Standard)COXApoptosisCyclooxygenaseInhibitorinhibitorinhibit

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