Difenoconazole-d₆ hydrochloride 

Difenoconazole-d₆ (hydrochloride) is deuterium labeled Difenoconazole. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth^[1][2].

448.76

C₁₉H₁₂D₆Cl₃N₃O₃

2748435-81-4

119446-68-3

ClC1=CC=C(C=C1)OC2=CC(Cl)=C(C=C2)C3(OC([2H])(C([2H])(O3)[2H])C([2H])([2H])[2H])CN4C=NC=N4.Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Mu X, et al. Evaluation of acute and developmental effects of difenoconazole via multiple stage zebrafish assays. Environ Pollut. 2013 Apr;175:147-57.  [Content Brief]

  [3]. Dong F, et al. Chiral triazole fungicide difenoconazole: absolute stereochemistry, stereoselective bioactivity, aquatic toxicity, and environmental behavior in vegetables and soil. Environ Sci Technol. 2013 Apr 2;47(7):3386-94.  [Content Brief]