Disodium phosphate

Cat. No.: HY-Y0308 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.

For research use only. We do not sell to patients.

Disodium phosphate Chemical Structure

CAS No. : 7558-79-4

Size	Stock	Quantity
Free Sample (0.1 - 0.5 mg)	Apply Now
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Other Forms of Disodium phosphate:

Phosphate dibasic-d₁ sodium Get quote
Sodium phosphate dibasic dihydrate, for molecular biology Get quote
Sodium phosphate dibasic dihydrate, meets analytical specification of Ph. Eur. BP Get quote
Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339 Get quote
Sodium phosphate dibasic, for cell culture Get quote
Sodium phosphate dibasic, for molecular biology Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	32 μM Compound: 24203	Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells	10.5281/zenodo.7355196

In Vitro

Disodium phosphate is also known as Na₂HPO₄ to adjust pH of liquid. Disodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

141.96

Formula

HNa₂O₄P

CAS No.

7558-79-4

Appearance

Solid

Color

White to off-white

SMILES

[Na2HPO4]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 200 mg/mL (1408.85 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.0442 mL	35.2212 mL	70.4424 mL
5 mM	1.4088 mL	7.0442 mL	14.0885 mL
10 mM	0.7044 mL	3.5221 mL	7.0442 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (244 KB)

Handling Instructions (2659 KB)

References

[1]. Baldus M, et al. Structure investigation on anhydrous disodium hydrogen phosphate using solid-state NMR and X-ray techniques[J]. Journal of the American Chemical Society, 1995, 117(18): 5141-5147.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	7.0442 mL	35.2212 mL	70.4424 mL	176.1059 mL
	5 mM	1.4088 mL	7.0442 mL	14.0885 mL	35.2212 mL
	10 mM	0.7044 mL	3.5221 mL	7.0442 mL	17.6106 mL
	15 mM	0.4696 mL	2.3481 mL	4.6962 mL	11.7404 mL
	20 mM	0.3522 mL	1.7611 mL	3.5221 mL	8.8053 mL
	25 mM	0.2818 mL	1.4088 mL	2.8177 mL	7.0442 mL
	30 mM	0.2348 mL	1.1740 mL	2.3481 mL	5.8702 mL
	40 mM	0.1761 mL	0.8805 mL	1.7611 mL	4.4026 mL
	50 mM	0.1409 mL	0.7044 mL	1.4088 mL	3.5221 mL
	60 mM	0.1174 mL	0.5870 mL	1.1740 mL	2.9351 mL
	80 mM	0.0881 mL	0.4403 mL	0.8805 mL	2.2013 mL
	100 mM	0.0704 mL	0.3522 mL	0.7044 mL	1.7611 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.