DL-dithiothreitol-d₆ (Synonyms: DTT-d₆)

Cat. No.: HY-15917S2 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DL-dithiothreitol-d₆ is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reducing agent with anti-disulfide activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond.

For research use only. We do not sell to patients.

DL-dithiothreitol-d<sub>6</sub> Chemical Structure

DL-dithiothreitol-d₆ Chemical Structure

CAS No. : 850153-85-4

Size	Price	Stock	Quantity
1 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 340	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of DL-dithiothreitol-d₆:

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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

160.29

Formula

C₄H₄D₆O₂S₂

CAS No.

850153-85-4

Unlabeled CAS

3483-12-3

Appearance

Solid

Color

White to off-white

SMILES

SC([2H])([2H])[C@](O)([2H])[C@@](O)([2H])C([2H])([2H])S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (623.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2387 mL	31.1935 mL	62.3869 mL
5 mM	1.2477 mL	6.2387 mL	12.4774 mL
10 mM	0.6239 mL	3.1193 mL	6.2387 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (254 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2387 mL	31.1935 mL	62.3869 mL	155.9673 mL
	5 mM	1.2477 mL	6.2387 mL	12.4774 mL	31.1935 mL
	10 mM	0.6239 mL	3.1193 mL	6.2387 mL	15.5967 mL
	15 mM	0.4159 mL	2.0796 mL	4.1591 mL	10.3978 mL
	20 mM	0.3119 mL	1.5597 mL	3.1193 mL	7.7984 mL
	25 mM	0.2495 mL	1.2477 mL	2.4955 mL	6.2387 mL
	30 mM	0.2080 mL	1.0398 mL	2.0796 mL	5.1989 mL
	40 mM	0.1560 mL	0.7798 mL	1.5597 mL	3.8992 mL
	50 mM	0.1248 mL	0.6239 mL	1.2477 mL	3.1193 mL
	60 mM	0.1040 mL	0.5199 mL	1.0398 mL	2.5995 mL
	80 mM	0.0780 mL	0.3899 mL	0.7798 mL	1.9496 mL
	100 mM	0.0624 mL	0.3119 mL	0.6239 mL	1.5597 mL

DL-dithiothreitol-d₆ Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-dithiothreitol-d₆850153-85-4DTT-d₆Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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DL-dithiothreitol-d6 (Synonyms: DTT-d6)

Other Forms of DL-dithiothreitol-d6:

DL-dithiothreitol-d6 Related Antibodies