2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. DL-Glutamic acid-d5

DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

For research use only. We do not sell to patients.

DL-Glutamic acid-d<sub>5</sub> Chemical Structure

DL-Glutamic acid-d5 Chemical Structure

CAS No. : 14341-79-8

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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Glutamic acid-d5:

DL-Glutamic acid-d5 Related Antibodies

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Description

DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DL-Glutamic acid-d5 Related Antibodies
Molecular Weight

152.16

Formula

C5H4D5NO4
CAS No.
Unlabeled CAS

617-65-2
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C(N)([2H])C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (164.30 mM; Need ultrasonic)

DMSO : 1 mg/mL (6.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5720 mL 32.8601 mL 65.7203 mL
5 mM 1.3144 mL 6.5720 mL 13.1441 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.68%

COA (250 KB) HNMR (529 KB) RP-HPLC (902 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 6.5720 mL 32.8601 mL 65.7203 mL 164.3007 mL
5 mM 1.3144 mL 6.5720 mL 13.1441 mL 32.8601 mL
H2O 10 mM 0.6572 mL 3.2860 mL 6.5720 mL 16.4301 mL
15 mM 0.4381 mL 2.1907 mL 4.3814 mL 10.9534 mL
20 mM 0.3286 mL 1.6430 mL 3.2860 mL 8.2150 mL
25 mM 0.2629 mL 1.3144 mL 2.6288 mL 6.5720 mL
30 mM 0.2191 mL 1.0953 mL 2.1907 mL 5.4767 mL
40 mM 0.1643 mL 0.8215 mL 1.6430 mL 4.1075 mL
50 mM 0.1314 mL 0.6572 mL 1.3144 mL 3.2860 mL
60 mM 0.1095 mL 0.5477 mL 1.0953 mL 2.7383 mL
80 mM 0.0822 mL 0.4108 mL 0.8215 mL 2.0538 mL
100 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.6430 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DL-Glutamic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-Glutamic acid-d514341-79-8Isotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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