DL-Homocysteine thiolactone-d₄ hydrochloride

Name: DL-Homocysteine thiolactone-d 4 hydrochloride
Brand: MedChemExpress
SKU: HY-101404S
Rating: 4.5 (1 reviews)

Cat. No.: HY-101404S Purity: 99.83%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

For research use only. We do not sell to patients.

DL-Homocysteine thiolactone-d<sub>4</sub> hydrochloride Chemical Structure

DL-Homocysteine thiolactone-d₄ hydrochloride Chemical Structure

CAS No. : 1219805-31-8

Size	Price	Stock	Quantity
1 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Homocysteine thiolactone-d₄ hydrochloride:

DL-Homocysteine thiolactone hydrochloride Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

157.66

Formula

C₄H₄D₄ClNOS

CAS No.

1219805-31-8

Unlabeled CAS

6038-19-3

Appearance

Solid

Color

White to off-white

SMILES

NC1C(SC([2H])([2H])C1([2H])[2H])=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (317.14 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.3428 mL	31.7138 mL	63.4276 mL
5 mM	1.2686 mL	6.3428 mL	12.6855 mL
10 mM	0.6343 mL	3.1714 mL	6.3428 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.83%

Select Batch:

Data Sheet (273 KB) SDS (251 KB)

COA (250 KB) HNMR (240 KB) RP-HPLC (895 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Yoshihiko INAMORI, et al. Root-growth Inhibition by DL-Homocysteine Thiolactone and Its Related Compounds. Biosci. Biotech. Biochem., 59 (3), 523-525, 1995.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.3428 mL	31.7138 mL	63.4276 mL	158.5691 mL
	5 mM	1.2686 mL	6.3428 mL	12.6855 mL	31.7138 mL
	10 mM	0.6343 mL	3.1714 mL	6.3428 mL	15.8569 mL
	15 mM	0.4229 mL	2.1143 mL	4.2285 mL	10.5713 mL
	20 mM	0.3171 mL	1.5857 mL	3.1714 mL	7.9285 mL
	25 mM	0.2537 mL	1.2686 mL	2.5371 mL	6.3428 mL
	30 mM	0.2114 mL	1.0571 mL	2.1143 mL	5.2856 mL
	40 mM	0.1586 mL	0.7928 mL	1.5857 mL	3.9642 mL
	50 mM	0.1269 mL	0.6343 mL	1.2686 mL	3.1714 mL
	60 mM	0.1057 mL	0.5286 mL	1.0571 mL	2.6428 mL
	80 mM	0.0793 mL	0.3964 mL	0.7928 mL	1.9821 mL
	100 mM	0.0634 mL	0.3171 mL	0.6343 mL	1.5857 mL