Dopamine-d₃ hydrochloride (Synonyms: ASL279-d₃)

Cat. No.: HY-B0451AS4 Purity: 99.30%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Dopamine-d₃ (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1].

For research use only. We do not sell to patients.

Dopamine-d<sub>3</sub> hydrochloride Chemical Structure

Dopamine-d₃ hydrochloride Chemical Structure

CAS No. : 53587-30-7

Size	Price	Stock	Quantity
1 mg	USD 65	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 195	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Description

Dopamine-d₃ (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

192.66

Formula

C₈H₉D₃ClNO₂

CAS No.

53587-30-7

Unlabeled CAS

62-31-7

Appearance

Solid

Color

White to off-white

SMILES

NCCC1=C([2H])C(O)=C(C([2H])=C1[2H])O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (259.52 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.1905 mL	25.9525 mL	51.9049 mL
5 mM	1.0381 mL	5.1905 mL	10.3810 mL
10 mM	0.5190 mL	2.5952 mL	5.1905 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.30%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (249 KB) HNMR (303 KB) RP-HPLC (232 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.1905 mL	25.9525 mL	51.9049 mL	129.7623 mL
	5 mM	1.0381 mL	5.1905 mL	10.3810 mL	25.9525 mL
	10 mM	0.5190 mL	2.5952 mL	5.1905 mL	12.9762 mL
	15 mM	0.3460 mL	1.7302 mL	3.4603 mL	8.6508 mL
	20 mM	0.2595 mL	1.2976 mL	2.5952 mL	6.4881 mL
	25 mM	0.2076 mL	1.0381 mL	2.0762 mL	5.1905 mL
	30 mM	0.1730 mL	0.8651 mL	1.7302 mL	4.3254 mL
	40 mM	0.1298 mL	0.6488 mL	1.2976 mL	3.2441 mL
	50 mM	0.1038 mL	0.5190 mL	1.0381 mL	2.5952 mL
	60 mM	0.0865 mL	0.4325 mL	0.8651 mL	2.1627 mL
	80 mM	0.0649 mL	0.3244 mL	0.6488 mL	1.6220 mL
	100 mM	0.0519 mL	0.2595 mL	0.5190 mL	1.2976 mL

Dopamine-d₃ hydrochloride Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dopamine-d₃53587-30-7ASL279-d₃Isotope-Labeled CompoundsOthersInhibitorinhibitorinhibit

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Dopamine-d3 hydrochloride (Synonyms: ASL279-d3)

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