2. PROTAC
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  4. Dovitinib-RIBOTAC TFA

Dovitinib RIBOTAC TFA is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

For research use only. We do not sell to patients.

Dovitinib-RIBOTAC TFA Chemical Structure

Dovitinib-RIBOTAC TFA Chemical Structure

CAS No. : 2759351-69-2

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1 mg USD 400 In-stock
5 mg USD 1280 In-stock
10 mg USD 2050 In-stock
25 mg USD 4250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Dovitinib-RIBOTAC TFA:

Dovitinib-RIBOTAC TFA Related Antibodies

Top Publications Citing Use of Products

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Description

Dovitinib RIBOTAC TFA is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

Molecular Weight

1120.13

Formula

C53H57F4N9O12S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (89.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8928 mL 4.4638 mL 8.9275 mL
5 mM 0.1786 mL 0.8928 mL 1.7855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8928 mL 4.4638 mL 8.9275 mL 22.3188 mL
5 mM 0.1786 mL 0.8928 mL 1.7855 mL 4.4638 mL
10 mM 0.0893 mL 0.4464 mL 0.8928 mL 2.2319 mL
15 mM 0.0595 mL 0.2976 mL 0.5952 mL 1.4879 mL
20 mM 0.0446 mL 0.2232 mL 0.4464 mL 1.1159 mL
25 mM 0.0357 mL 0.1786 mL 0.3571 mL 0.8928 mL
30 mM 0.0298 mL 0.1488 mL 0.2976 mL 0.7440 mL
40 mM 0.0223 mL 0.1116 mL 0.2232 mL 0.5580 mL
50 mM 0.0179 mL 0.0893 mL 0.1786 mL 0.4464 mL
60 mM 0.0149 mL 0.0744 mL 0.1488 mL 0.3720 mL
80 mM 0.0112 mL 0.0558 mL 0.1116 mL 0.2790 mL
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Dovitinib-RIBOTAC TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dovitinib-RIBOTAC2759351-69-2PROTACsInhibitorinhibitorinhibit

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