Doxorubicin hydrochloride (Standard)

Cat. No.: HY-15142R Purity: ≥98%: FAQs
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Doxorubicin (hydrochloride) (Standard) is the analytical standard of Doxorubicin (hydrochloride). This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.

For research use only. We do not sell to patients.

Doxorubicin hydrochloride (Standard) Chemical Structure

CAS No. : 25316-40-9

Size	Price	Stock	Quantity
5 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 65	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE Doxorubicin hydrochloride (Standard)

•Signal Transduct Target Ther. 2024 Oct 16;9(1):273. [Abstract]

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Description	Doxorubicin (hydrochloride) (Standard) is the analytical standard of Doxorubicin (hydrochloride). This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
Molecular Weight	579.98
Formula	C₂₇H₃₀ClNO₁₁
CAS No.	25316-40-9
Appearance	Solid
Color	Orange to red
SMILES	COC1=C2C(C(C3=C(C2=O)C(O)=C4C(C[C@](O)(C[C@@H]4O[C@]5(C[C@@H]([C@@H]([C@@H](O5)C)O)N)[H])C(CO)=O)=C3O)=O)=CC=C1.[H]Cl
Structure Classification	Quinones Anthraquinones
Initial Source	Microorganisms
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	SDS (557 KB) Handling Instructions (2659 KB)