1. Antibody-drug Conjugate/ADC Related
  2. Radionuclide-Drug Conjugates (RDCs)
  3. DTPA anhydride

DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.

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DTPA anhydride Chemical Structure

DTPA anhydride Chemical Structure

CAS No. : 23911-26-4

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Description

DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

357.32

Formula

C14H19N3O8

CAS No.
Appearance

Solid

SMILES

O=C(CN(CCN1CC(OC(C1)=O)=O)CCN2CC(OC(C2)=O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DTPA anhydride
Cat. No.:
HY-W011118
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