2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin DNA Alkylator/Crosslinker
  4. Duocarmycin Analog

Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin.

For research use only. We do not sell to patients.

Duocarmycin Analog Chemical Structure

Duocarmycin Analog Chemical Structure

CAS No. : 372954-15-9

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Based on 1 publication(s) in Google Scholar

Duocarmycin Analog Related Antibodies

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Description

Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin[1].

IC50 & Target[1]

Duocarmycins

 

DNA alkylator

 

In Vitro

ADC cytotoxins (also known as payloads) are cytotoxic agents that induce target cell death in Antibody Drug Conjugates (ADCs). An ADC is a targeted agent composed with a monoclonal antibody, a linker and a cytotoxin. The cytotoxin is the most important component as it determines the potency to kill cancer cells of an ADC.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Duocarmycin Analog Related Antibodies
Molecular Weight

611.09

Formula

C34H31ClN4O5
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(OC(C)(C)C)NC1=CC=C(C(NC2=CC3=C(NC(C(N4C[C@@H](CCl)C5=C4C=C(O)C6=CC=CC=C56)=O)=C3)C=C2)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Duocarmycin Analog Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Duocarmycin372954-15-9ADC CytotoxinDNA Alkylator/CrosslinkerADC PayloadInhibitorinhibitorinhibit

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Duocarmycin Analog
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HY-129355
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