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dWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ(ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD).

For research use only. We do not sell to patients.

dWIZ-1 Chemical Structure

dWIZ-1 Chemical Structure

Size Price Stock Quantity
1 mg USD 425 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
5 mg USD 1060 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
10 mg USD 1812 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
25 mg USD 3987 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
50 mg USD 6620 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
100 mg   Get quote  
200 mg   Get quote  
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Description

dWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ(ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD)[1].

Molecular Weight

399.48

Formula

C22H29N3O4

SMILES

O=C([C@@H](N(CC1=C2C=CC(O[C@@H]([C@@H]3N(CC)CCCC3)C)=C1)C2=O)CC4)NC4=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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dWIZ-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
dWIZ-1
Cat. No.:
HY-159098
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