1. Peptides
  2. Peptide and Derivatives
  3. Inhibitors and Substrates
  4. Enzyme Substrates
  5. DYRKtide

DYRKtide is a biological active peptide. (Dyrktide is designed as the optimal substrate sequence efficiently phosphorylated by DYRK1A, which is a dual-specificity protein kinase that is thought to be involved in brain development.)

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DYRKtide Chemical Structure

DYRKtide Chemical Structure

CAS No. : 2250228-51-2

Size Price Stock Quantity
1 mg USD 120 In-stock
5 mg USD 300 In-stock
10 mg USD 450 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

DYRKtide is a biological active peptide. (Dyrktide is designed as the optimal substrate sequence efficiently phosphorylated by DYRK1A, which is a dual-specificity protein kinase that is thought to be involved in brain development.)

Molecular Weight

1791.11

Formula

C79H135N31O17

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Arg-Arg-Phe-Arg-Pro-Ala-Ser-Pro-Leu-Arg-Gly-Pro-Pro-Lys

Sequence Shortening

RRRFRPASPLRGPPK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (55.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5583 mL 2.7916 mL 5.5831 mL
5 mM 0.1117 mL 0.5583 mL 1.1166 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5583 mL 2.7916 mL 5.5831 mL 13.9578 mL
5 mM 0.1117 mL 0.5583 mL 1.1166 mL 2.7916 mL
10 mM 0.0558 mL 0.2792 mL 0.5583 mL 1.3958 mL
15 mM 0.0372 mL 0.1861 mL 0.3722 mL 0.9305 mL
20 mM 0.0279 mL 0.1396 mL 0.2792 mL 0.6979 mL
25 mM 0.0223 mL 0.1117 mL 0.2233 mL 0.5583 mL
30 mM 0.0186 mL 0.0931 mL 0.1861 mL 0.4653 mL
40 mM 0.0140 mL 0.0698 mL 0.1396 mL 0.3489 mL
50 mM 0.0112 mL 0.0558 mL 0.1117 mL 0.2792 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DYRKtide
Cat. No.:
HY-P5430
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