E-Cadherin activator-1

Cat. No.: HY-164712 Purity: 99.01%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

E-cadherin activator-1 (Compound 13m) is an E-Cadherin activator. E-cadherin activator-1 can be used in the study of colorectal carcinoma.

For research use only. We do not sell to patients.

E-Cadherin activator-1 Chemical Structure

CAS No. : 912787-60-1

Size	Price	Stock	Quantity
5 mg	USD 94	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

E-cadherin activator-1 (Compound 13m) is an E-Cadherin activator. E-cadherin activator-1 can be used in the study of colorectal carcinoma^[1].

Molecular Weight

386.83

Formula

C₂₀H₁₉ClN₂O₄

CAS No.

912787-60-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NOC(C2=CC=C(Cl)C=C2)=C1)NCCC3=CC=C(C(OC)=C3)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL (32.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5851 mL	12.9256 mL	25.8512 mL
5 mM	0.5170 mL	2.5851 mL	5.1702 mL
10 mM	0.2585 mL	1.2926 mL	2.5851 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.01%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (246 KB) HNMR (259 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Stoops SL, et, al. Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells. ACS Chem Biol. 2011 May 20;6(5):452-65. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5851 mL	12.9256 mL	25.8511 mL	64.6279 mL
	5 mM	0.5170 mL	2.5851 mL	5.1702 mL	12.9256 mL
	10 mM	0.2585 mL	1.2926 mL	2.5851 mL	6.4628 mL
	15 mM	0.1723 mL	0.8617 mL	1.7234 mL	4.3085 mL
	20 mM	0.1293 mL	0.6463 mL	1.2926 mL	3.2314 mL
	25 mM	0.1034 mL	0.5170 mL	1.0340 mL	2.5851 mL
	30 mM	0.0862 mL	0.4309 mL	0.8617 mL	2.1543 mL