2. Vitamin D Related/Nuclear Receptor
  3. VD/VDR
  4. Elocalcitol

Elocalcitol  (Synonyms: BXL-628; Ro-26-9228)

Cat. No.: HY-32345 Purity: 99.2%
SDS COA Handling Instructions

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Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells.

For research use only. We do not sell to patients.

Elocalcitol Chemical Structure

Elocalcitol Chemical Structure

CAS No. : 199798-84-0

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Based on 1 publication(s) in Google Scholar

Elocalcitol Related Antibodies

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Description

Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells[1][2].

Molecular Weight

442.65

Formula

C29H43FO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC=C2[C@@H](C)C/C=C/C(CC)(O)CC)([H])/C(CCC1)=C/C=C3C([C@H](C[C@@H](C\3)O)F)=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (67.77 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2591 mL 11.2956 mL 22.5912 mL
5 mM 0.4518 mL 2.2591 mL 4.5182 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.2%

SDS (251 KB)

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2591 mL 11.2956 mL 22.5912 mL 56.4780 mL
5 mM 0.4518 mL 2.2591 mL 4.5182 mL 11.2956 mL
10 mM 0.2259 mL 1.1296 mL 2.2591 mL 5.6478 mL
15 mM 0.1506 mL 0.7530 mL 1.5061 mL 3.7652 mL
20 mM 0.1130 mL 0.5648 mL 1.1296 mL 2.8239 mL
25 mM 0.0904 mL 0.4518 mL 0.9036 mL 2.2591 mL
30 mM 0.0753 mL 0.3765 mL 0.7530 mL 1.8826 mL
40 mM 0.0565 mL 0.2824 mL 0.5648 mL 1.4120 mL
50 mM 0.0452 mL 0.2259 mL 0.4518 mL 1.1296 mL
60 mM 0.0377 mL 0.1883 mL 0.3765 mL 0.9413 mL
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Elocalcitol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elocalcitol199798-84-0BXL-628 Ro-26-9228BXL628BXL 628VD/VDRVitamin DVitamin D receptorendometriosisinflammationprostateorally activeInhibitorinhibitorinhibit

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