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Elubiol  (Synonyms: Dichlorophenyl imidazoldioxolan)

Cat. No.: HY-121069 Purity: 98.69%
COA Handling Instructions

Elubiol (Dichlorophenyl imidazoldioxolan) has moderate sebum-inhibiting activity and can be used in the treatment of oily skin or dandruff.

For research use only. We do not sell to patients.

Elubiol Chemical Structure

Elubiol Chemical Structure

CAS No. : 67914-69-6

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Elubiol (Dichlorophenyl imidazoldioxolan) has moderate sebum-inhibiting activity and can be used in the treatment of oily skin or dandruff[1].

In Vitro

Elubiol (0.5 μM) reduces cholesterol production by 50% in human keratinocytes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

561.46

Formula

C27H30Cl2N4O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCN(C2=CC=C(OC[C@@H]3O[C@@](CN4C=CN=C4)(C5=CC=C(Cl)C=C5Cl)OC3)C=C2)CC1)OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (311.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7811 mL 8.9054 mL 17.8107 mL
5 mM 0.3562 mL 1.7811 mL 3.5621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7811 mL 8.9054 mL 17.8107 mL 44.5268 mL
5 mM 0.3562 mL 1.7811 mL 3.5621 mL 8.9054 mL
10 mM 0.1781 mL 0.8905 mL 1.7811 mL 4.4527 mL
15 mM 0.1187 mL 0.5937 mL 1.1874 mL 2.9685 mL
20 mM 0.0891 mL 0.4453 mL 0.8905 mL 2.2263 mL
25 mM 0.0712 mL 0.3562 mL 0.7124 mL 1.7811 mL
30 mM 0.0594 mL 0.2968 mL 0.5937 mL 1.4842 mL
40 mM 0.0445 mL 0.2226 mL 0.4453 mL 1.1132 mL
50 mM 0.0356 mL 0.1781 mL 0.3562 mL 0.8905 mL
60 mM 0.0297 mL 0.1484 mL 0.2968 mL 0.7421 mL
80 mM 0.0223 mL 0.1113 mL 0.2226 mL 0.5566 mL
100 mM 0.0178 mL 0.0891 mL 0.1781 mL 0.4453 mL
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Elubiol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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