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  4. Inhibitors and Substrates
  5. Endotoxin inhibitor

Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality.

For research use only. We do not sell to patients.

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Endotoxin inhibitor Chemical Structure

Endotoxin inhibitor Chemical Structure

CAS No. : 147396-10-9

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Other Forms of Endotoxin inhibitor:

Endotoxin inhibitor Related Antibodies

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Description

Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1].

In Vivo

Endotoxin inhibitor (i.p., 0.5 mg/kg) significantly attenuates heat exposure-induced increases in mRNA for IL-1β, COX-2, IκB-β, and LPS activity, as well as heat exposure-induced hypothermia and plasma ACTH and catecholamine responses in aged rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1224.58

Formula

C55H97N15O12S2
CAS No.
Sequence Shortening

KTKCKFLKKC (Disulfide bridge: Cys4-Cys10)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Endotoxin inhibitor Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Endotoxin inhibitor147396-10-9Otherspeptidelipid ALPSfebrile responseInhibitorinhibitorinhibit

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