2. Immunology/Inflammation
  3. CD3 CD20
  4. Epcoritamab

Epcoritamab  (Synonyms: GEN3013)

Cat. No.: HY-P99931 Purity: 99.84%
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Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines.

For research use only. We do not sell to patients.

CAS No. : 2134641-34-0

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Based on 1 publication(s) in Google Scholar

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Epcoritamab Related Antibodies

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Description

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1].

Isotype

Ig(G1-kappa_G1-lambda2)
Species

Human; Chimeric
In Vitro

Epcoritamab (30 ng/mL) induces potent cytotoxicity in the presence of healthy donor peripheral blood mononuclear cells (PBMCs)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Epcoritamab Related Antibodies
Clinical Trial
Molecular Weight

146280.00

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Epcoritamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Ig(G1-kappa_G1-lambda2)
Biological Activity
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Epcoritamab. The EC50 for this effect is 2.85 ng/mL.
Purity & Documentation
References
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Epcoritamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epcoritamab2134641-34-0GEN3013GEN 3013GEN-3013CD3CD20Cluster of differentiation 3peripheral blood mononuclear cellsPBMCInhibitorinhibitorinhibit

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