2. Immunology/Inflammation
  3. CD3 CD20
  4. Epcoritamab

Epcoritamab  (Synonyms: GEN3013)

Cat. No.: HY-P99931 Purity: 99.84%
COA

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Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines.

For research use only. We do not sell to patients.

CAS No. : 2134641-34-0

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1 mg USD 650 In-stock
5 mg USD 1700 In-stock
10 mg USD 2720 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Epcoritamab Related Antibodies

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Description

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1].

Isotype

Ig(G1-kappa_G1-lambda2)
Species

Human; Chimeric
In Vitro

Epcoritamab (30 ng/mL) induces potent cytotoxicity in the presence of healthy donor peripheral blood mononuclear cells (PBMCs)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Epcoritamab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Epcoritamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Ig(G1-kappa_G1-lambda2)
Biological Activity
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Epcoritamab. The EC50 for this effect is 2.85 ng/mL.
Purity & Documentation
References
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Epcoritamab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epcoritamab2134641-34-0GEN3013GEN 3013GEN-3013CD3CD20Cluster of differentiation 3peripheral blood mononuclear cellsPBMCInhibitorinhibitorinhibit

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