2. Epigenetics
  3. Histone Methyltransferase
  4. EPZ030456

EPZ030456 is a potent and selective SMYD3 inhibitor with an IC50 of 48 nM. EPZ030456 can be used for cancer research.

For research use only. We do not sell to patients.

EPZ030456 Chemical Structure

EPZ030456 Chemical Structure

CAS No. : 1808011-23-5

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EPZ030456 Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

  • Biological Activity

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Description

EPZ030456 is a potent and selective SMYD3 inhibitor with an IC50 of 48 nM. EPZ030456 can be used for cancer research[1].

Molecular Weight

572.12

Formula

C28H34ClN5O4S
CAS No.
SMILES

O=S(N1[C@]2([H])C[C@H](C[C@@]1([H])CC2)NC(C3=C(Cl)C=C(NC(C4)=O)C4=C3)=O)(N5CCC(CC5)NCC6=CC=CC=C6)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EPZ030456 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EPZ0304561808011-23-5EPZ 030456EPZ-030456Histone MethyltransferaseSMYD3 InhibitorcancerInhibitorinhibitorinhibit

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