1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Esmolol

Esmolol is a potent and cardio-selective β-adrenergic blocker. Esmolol shows cardioprotection. Esmolol has the potential for the research of tachycardia with ischemic heart disease.

For research use only. We do not sell to patients.

Esmolol Chemical Structure

Esmolol Chemical Structure

CAS No. : 81147-92-4

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Description

Esmolol is a potent and cardio-selective β-adrenergic blocker. Esmolol shows cardioprotection. Esmolol has the potential for the research of tachycardia with ischemic heart disease[1][2].

IC50 & Target[2]

β-adrenoceptor

 

In Vivo

Esmolol (0.4, 0.8 mg/kg/h; Intraarterial continuous infusion for 120 min) shows cardioprotection in mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J wildtype mice[2]
Dosage: 0.4, 0.8 mg/kg/h
Administration: Intraarterial continuous infusion, 120 min; after 60 min of myocardial ischemia
Result: Showed robust cardioprotection with esmolol of 24.3%.
Molecular Weight

295.37

Formula

C16H25NO4

CAS No.
SMILES

O=C(OC)CCC1=CC=C(OCC(O)CNC(C)C)C=C1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Esmolol
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HY-B1392A
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