Esmolol

Cat. No.: HY-B1392A: FAQs
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Esmolol is a potent and cardio-selective β-adrenergic blocker. Esmolol shows cardioprotection. Esmolol has the potential for the research of tachycardia with ischemic heart disease.

For research use only. We do not sell to patients.

Esmolol Chemical Structure

CAS No. : 81147-92-4

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Other In-stock Forms of Esmolol:

Esmolol hydrochloride

Other Forms of Esmolol:

Esmolol hydrochloride In-stock

3 Publications Citing Use of MCE Esmolol

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α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
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Description

Esmolol is a potent and cardio-selective β-adrenergic blocker. Esmolol shows cardioprotection. Esmolol has the potential for the research of tachycardia with ischemic heart disease^[1]^[2].

IC₅₀ & Target^[2]

β-adrenoceptor

In Vivo

Esmolol (0.4, 0.8 mg/kg/h; Intraarterial continuous infusion for 120 min) shows cardioprotection in mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	C57BL/6J wildtype mice^[2]
Dosage:	0.4, 0.8 mg/kg/h
Administration:	Intraarterial continuous infusion, 120 min; after 60 min of myocardial ischemia
Result:	Showed robust cardioprotection with esmolol of 24.3%.

Molecular Weight

295.37

Formula

C₁₆H₂₅NO₄

CAS No.

81147-92-4

SMILES

O=C(OC)CCC1=CC=C(OCC(O)CNC(C)C)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Reves JG, et al. Esmolol for treatment of intraoperative tachycardia and/or hypertension in patients having cardiac operations. Bolus loading technique. J Thorac Cardiovasc Surg. 1990 Aug;100(2):221-7. [Content Brief]

Esmolol Related Classifications

Cardiovascular Disease

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Esmolol81147-92-4Adrenergic ReceptorBeta Receptorcardio-selectivecardioprotectiontachycardiaInhibitorinhibitorinhibit

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