2. Others Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Estrogen Receptor/ERR Endogenous Metabolite
  4. Estrone-d2-1

Estrone-d2-1  (Synonyms: E1-d2-1; Oestrone-d2-1)

Cat. No.: HY-B0234S4 Purity: ≥95.0%
COA Handling Instructions

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Estrone-d2-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

For research use only. We do not sell to patients.

Estrone-d<sub>2</sub>-1 Chemical Structure

Estrone-d2-1 Chemical Structure

CAS No. : 56588-58-0

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1 mg USD 76 In-stock
5 mg USD 227 Get quote
10 mg USD 363 Get quote
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Based on 1 publication(s) in Google Scholar

Other Forms of Estrone-d2-1:

Estrone-d2-1 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

Estrone-d2-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Estrone-d2-1 Related Antibodies
Molecular Weight

272.38

Formula

C18H20D2O2
CAS No.
Unlabeled CAS

53-16-7
Appearance

Solid

Color

White to off-white

SMILES

C[C@]1([C@](CC2([2H])[2H])([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (91.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6713 mL 18.3567 mL 36.7134 mL
5 mM 0.7343 mL 3.6713 mL 7.3427 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥95.0%

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6713 mL 18.3567 mL 36.7134 mL 91.7835 mL
5 mM 0.7343 mL 3.6713 mL 7.3427 mL 18.3567 mL
10 mM 0.3671 mL 1.8357 mL 3.6713 mL 9.1784 mL
15 mM 0.2448 mL 1.2238 mL 2.4476 mL 6.1189 mL
20 mM 0.1836 mL 0.9178 mL 1.8357 mL 4.5892 mL
25 mM 0.1469 mL 0.7343 mL 1.4685 mL 3.6713 mL
30 mM 0.1224 mL 0.6119 mL 1.2238 mL 3.0595 mL
40 mM 0.0918 mL 0.4589 mL 0.9178 mL 2.2946 mL
50 mM 0.0734 mL 0.3671 mL 0.7343 mL 1.8357 mL
60 mM 0.0612 mL 0.3059 mL 0.6119 mL 1.5297 mL
80 mM 0.0459 mL 0.2295 mL 0.4589 mL 1.1473 mL
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Estrone-d2-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrone-d2-156588-58-0E1-d2-1Oestrone-d2-1Isotope-Labeled CompoundsEstrogen Receptor/ERREndogenous MetaboliteInhibitorinhibitorinhibit

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