1. Others Anti-infection
  2. Isotope-Labeled Compounds Bacterial Antibiotic
  3. Ethambutol-d4

Ethambutol-d4  (Synonyms: Emb-d4)

Cat. No.: HY-B0535S Purity: 98.12%
COA Handling Instructions

Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

For research use only. We do not sell to patients.

Ethambutol-d<sub>4</sub> Chemical Structure

Ethambutol-d4 Chemical Structure

CAS No. : 1129526-19-7

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1 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

208.33

Formula

C10H20D4N2O2

CAS No.
Unlabeled CAS

1070-11-7

Appearance

Solid

Color

White to off-white

SMILES

CC[C@@H](CO)NC([2H])([2H])C([2H])([2H])N[C@H](CO)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (480.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8001 mL 24.0004 mL 48.0008 mL
5 mM 0.9600 mL 4.8001 mL 9.6002 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8001 mL 24.0004 mL 48.0008 mL 120.0019 mL
5 mM 0.9600 mL 4.8001 mL 9.6002 mL 24.0004 mL
10 mM 0.4800 mL 2.4000 mL 4.8001 mL 12.0002 mL
15 mM 0.3200 mL 1.6000 mL 3.2001 mL 8.0001 mL
20 mM 0.2400 mL 1.2000 mL 2.4000 mL 6.0001 mL
25 mM 0.1920 mL 0.9600 mL 1.9200 mL 4.8001 mL
30 mM 0.1600 mL 0.8000 mL 1.6000 mL 4.0001 mL
40 mM 0.1200 mL 0.6000 mL 1.2000 mL 3.0000 mL
50 mM 0.0960 mL 0.4800 mL 0.9600 mL 2.4000 mL
60 mM 0.0800 mL 0.4000 mL 0.8000 mL 2.0000 mL
80 mM 0.0600 mL 0.3000 mL 0.6000 mL 1.5000 mL
100 mM 0.0480 mL 0.2400 mL 0.4800 mL 1.2000 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ethambutol-d4
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