2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. Eucannabinolide

Eucannabinolide  (Synonyms: Hiyodorilactone A; Schkuhrin I)

Cat. No.: HY-118618
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Eucannabinolide is a STAT3 inhibitor. Eucannabinolide suppresses STAT3 activation at tyrosine 705, inhibiteds its translocation to nucleus, and decreases its DNA binding capacity. Eucannabinolide can be used for triple negative breast cancer (TNBC) diseases research.

For research use only. We do not sell to patients.

Eucannabinolide Chemical Structure

Eucannabinolide Chemical Structure

CAS No. : 38458-58-1

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Eucannabinolide Related Antibodies

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Description

Eucannabinolide is a STAT3 inhibitor. Eucannabinolide suppresses STAT3 activation at tyrosine 705, inhibiteds its translocation to nucleus, and decreases its DNA binding capacity. Eucannabinolide can be used for triple negative breast cancer (TNBC) diseases research[1].

Cellular Effect
Cell Line Type Value Description References
L6 IC50
7.8 μM
Compound: 8
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
[PMID: 29244495]
Molecular Weight

420.45

Formula

C22H28O8
CAS No.
SMILES

C/C(C[C@H]1OC(/C(CO)=C/CO)=O)=C/C[C@H](OC(C)=O)/C(C)=C\[C@@]([C@]1([H])C2=C)([H])OC2=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Eucannabinolide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eucannabinolide38458-58-1Hiyodorilactone A Schkuhrin ISTATcancerTNBCSTAT3Inhibitorinhibitorinhibit

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