Eupalinilide B

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Eupalinilide B is a guaiane type sesquiterpene lactone that can be found in Eupatorium lindleyanum. Eupalinilide B shows potent cytotoxicity against P-388 and A-549 tumor cell lines.

For research use only. We do not sell to patients.

Eupalinilide B Chemical Structure

CAS No. : 757202-08-7

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Description

Eupalinilide B is a guaiane type sesquiterpene lactone that can be found in Eupatorium lindleyanum. Eupalinilide B shows potent cytotoxicity against P-388 and A-549 tumor cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.75 μg/mL Compound: 2, Eupalinilide B	Cytotoxicity against human A549 cells after 24 hrs Cytotoxicity against human A549 cells after 24 hrs	[PMID: 15387644]
P388	IC₅₀	0.21 μg/mL Compound: 2, Eupalinilide B	Cytotoxicity against mouse P388 cells after 24 hrs Cytotoxicity against mouse P388 cells after 24 hrs	[PMID: 15387644]

In Vitro

Eupalinilide B (0.1-10 μM) shows potent cytotoxicity against A-549, BGC-823, SMMC-7721 and HL-60 tumour cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

360.40

Formula

C₂₀H₂₄O₆

CAS No.

757202-08-7

SMILES

C[C@@]1([C@]([C@@]2([H])C=C1)([H])[C@](O3)([H])[C@@](C(C3=O)=C)([H])[C@H](OC(/C(C)=C/CO)=O)CC2=C)O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Huo J, et, al. Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. J Nat Prod. 2004 Sep;67(9):1470-5. [Content Brief]

Eupalinilide B Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eupalinilide B757202-08-7OthersguaianesesquiterpenelactonecytotoxicitytumorInhibitorinhibitorinhibit

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