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  4. FAP Ligand 1

FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers.

For research use only. We do not sell to patients.

FAP Ligand 1 Chemical Structure

FAP Ligand 1 Chemical Structure

CAS No. : 2230625-76-8

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1 mg USD 510 In-stock
5 mg USD 1280 In-stock
10 mg USD 2040 In-stock
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Based on 1 publication(s) in Google Scholar

FAP Ligand 1 Related Antibodies

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Description

FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers[1].

Molecular Weight

337.32

Formula

C15H17F2N5O2
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(C1=CC=NC(CN)=C1)N[C@@H](C)C(N2[C@@H](CC(F)(C2)F)C#N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 75 mg/mL (222.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9645 mL 14.8227 mL 29.6454 mL
5 mM 0.5929 mL 2.9645 mL 5.9291 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9645 mL 14.8227 mL 29.6454 mL 74.1136 mL
5 mM 0.5929 mL 2.9645 mL 5.9291 mL 14.8227 mL
10 mM 0.2965 mL 1.4823 mL 2.9645 mL 7.4114 mL
15 mM 0.1976 mL 0.9882 mL 1.9764 mL 4.9409 mL
20 mM 0.1482 mL 0.7411 mL 1.4823 mL 3.7057 mL
25 mM 0.1186 mL 0.5929 mL 1.1858 mL 2.9645 mL
30 mM 0.0988 mL 0.4941 mL 0.9882 mL 2.4705 mL
40 mM 0.0741 mL 0.3706 mL 0.7411 mL 1.8528 mL
50 mM 0.0593 mL 0.2965 mL 0.5929 mL 1.4823 mL
60 mM 0.0494 mL 0.2470 mL 0.4941 mL 1.2352 mL
80 mM 0.0371 mL 0.1853 mL 0.3706 mL 0.9264 mL
100 mM 0.0296 mL 0.1482 mL 0.2965 mL 0.7411 mL
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FAP Ligand 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAP Ligand 12230625-76-8FAP Ligand1FAP Ligand-1OthersInhibitorinhibitorinhibit

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