2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Immunology/Inflammation
  3. EGFR PD-1/PD-L1
  4. Fidasimtamab

Fidasimtamab  (Synonyms: IBI-315; BH2950)

Cat. No.: HY-P99618 Purity: ≥95.0%
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Fidasimtamab (IBI-315; BH2950) is a recombinant human IgG1 bispecific antibody that targets, binds and inhibits both HER2 and PD-1 and their downstream signalling pathways, and links PD-1 expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity.

For research use only. We do not sell to patients.

CAS No. : 2377419-89-9

Size Price Stock Quantity
1 mg USD 450 In-stock
5 mg USD 1170 In-stock
10 mg USD 1870 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Fidasimtamab Related Antibodies

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Description

Fidasimtamab (IBI-315; BH2950) is a recombinant human IgG1 bispecific antibody that targets, binds and inhibits both HER2 and PD-1 and their downstream signalling pathways, and links PD-1 expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity[1].
Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Bispecific; Humanized

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Fidasimtamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation

Purity: ≥95.0%

SDS (251 KB)

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Fidasimtamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fidasimtamab2377419-89-9IBI-315 BH2950IBI315IBI 315BH2950BH 2950BH-2950EGFRPD-1/PD-L1Epidermal growth factor receptorErbB-1HER1PD-1/Programmed death-ligand 1IgG1bispecific antibodyHER2PD-1immunosuppressiveantitumorInhibitorinhibitorinhibit

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