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  3. Fluorescent Dye
  4. FITC-C6-DEVD-FMK

FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor.

For research use only. We do not sell to patients.

FITC-C6-DEVD-FMK Chemical Structure

FITC-C6-DEVD-FMK Chemical Structure

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1 mg USD 1435 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
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Based on 1 publication(s) in Google Scholar

FITC-C6-DEVD-FMK Related Antibodies

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Description

FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor[1].

Molecular Weight

994.99

Formula

C46H51FN6O16S
Appearance

Oil

Color

Pink to red

Emission (Em)

520
Excitation (Ex)

488
SMILES

O=C1C=CC(C(O2)=C1)=C(C3=C(C(O)=O)C=C(NC(NCCCCCC(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(CF)=O)=O)=O)=O)=O)=S)C=C3)C4=C2C=C(O)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 17.91 mg/mL (18.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0050 mL 5.0252 mL 10.0504 mL
5 mM 0.2010 mL 1.0050 mL 2.0101 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0050 mL 5.0252 mL 10.0504 mL 25.1259 mL
5 mM 0.2010 mL 1.0050 mL 2.0101 mL 5.0252 mL
10 mM 0.1005 mL 0.5025 mL 1.0050 mL 2.5126 mL
15 mM 0.0670 mL 0.3350 mL 0.6700 mL 1.6751 mL
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FITC-C6-DEVD-FMK Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FITC-C6-DEVD-FMKFluorescent Dyefluorescently labeled caspase-3 inhibitoractive caspase-3Inhibitorinhibitorinhibit

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