2. Stem Cell/Wnt
  3. Wnt
  4. Fluc-IN-1

Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay).

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Fluc-IN-1 Chemical Structure

Fluc-IN-1 Chemical Structure

CAS No. : 2940242-10-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
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Based on 1 publication(s) in Google Scholar

Fluc-IN-1 Related Antibodies

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Description

Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay)[1].

IC50 & Target

IC50: 25 nM (firefly luciferase)
Molecular Weight

473.61

Formula

C26H23N3O2S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(C)C=C1C)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 116.67 mg/mL (246.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1114 mL 10.5572 mL 21.1144 mL
5 mM 0.4223 mL 2.1114 mL 4.2229 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1114 mL 10.5572 mL 21.1144 mL 52.7860 mL
5 mM 0.4223 mL 2.1114 mL 4.2229 mL 10.5572 mL
10 mM 0.2111 mL 1.0557 mL 2.1114 mL 5.2786 mL
15 mM 0.1408 mL 0.7038 mL 1.4076 mL 3.5191 mL
20 mM 0.1056 mL 0.5279 mL 1.0557 mL 2.6393 mL
25 mM 0.0845 mL 0.4223 mL 0.8446 mL 2.1114 mL
30 mM 0.0704 mL 0.3519 mL 0.7038 mL 1.7595 mL
40 mM 0.0528 mL 0.2639 mL 0.5279 mL 1.3197 mL
50 mM 0.0422 mL 0.2111 mL 0.4223 mL 1.0557 mL
60 mM 0.0352 mL 0.1760 mL 0.3519 mL 0.8798 mL
80 mM 0.0264 mL 0.1320 mL 0.2639 mL 0.6598 mL
100 mM 0.0211 mL 0.1056 mL 0.2111 mL 0.5279 mL
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Fluc-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluc-IN-12940242-10-2WntInhibitorinhibitorinhibit

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