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Fluridone is a herbicide, particularly to eliminate aquatic plant growth in water reservoirs and irrigation channels. Fluridone is a potent Abscisic acid (ABA) biosynthesis inhibitor, and has anti-inflammatory effects.

For research use only. We do not sell to patients.

Fluridone Chemical Structure

Fluridone Chemical Structure

CAS No. : 59756-60-4

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Based on 1 publication(s) in Google Scholar

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Fluridone Related Antibodies

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  • Purity & Documentation

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Description

Fluridone is a herbicide, particularly to eliminate aquatic plant growth in water reservoirs and irrigation channels. Fluridone is a potent Abscisic acid (ABA) biosynthesis inhibitor, and has anti-inflammatory effects[1][2].

In Vitro

Fluridone (0.5-50 μM; for 4 days) inhibits the proliferation of aortic smooth muscle cells and reduces proliferation and cytokine release by human activated lymphocytes. In stimulated human monocytes, Fluridone inhibits COX-2 expression and the release of MCP-1 and prostaglandin-E2. Fluridone also inhibits the release from stimulated human monocytes of abscisic acid[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fluridone Related Antibodies

Cell Proliferation Assay[1]

Cell Line: Lymphocytes
Concentration: 0.5 μM, 2 μM, 5 μM, 50 μM
Incubation Time: for 4 days
Result: Inhibited the proliferation of aortic smooth muscle cells.
In Vivo

Fluridone (8.25 mg/kg; i.p.; once) reduces peritoneal inflammation in Zymosan-treated mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male CD mice (20-22 g) treated with Zymosan[1]
Dosage: 8.25 mg/kg
Administration: i.p.; once
Result: Reduced peritoneal inflammation in Zymosan-treated mice.
Molecular Weight

329.32

Formula

C19H14F3NO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C(C2=CC=CC=C2)=CN(C)C=C1C3=CC=CC(C(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (759.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0366 mL 15.1828 mL 30.3656 mL
5 mM 0.6073 mL 3.0366 mL 6.0731 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.79%

COA (246 KB) HNMR (240 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0366 mL 15.1828 mL 30.3656 mL 75.9140 mL
5 mM 0.6073 mL 3.0366 mL 6.0731 mL 15.1828 mL
10 mM 0.3037 mL 1.5183 mL 3.0366 mL 7.5914 mL
15 mM 0.2024 mL 1.0122 mL 2.0244 mL 5.0609 mL
20 mM 0.1518 mL 0.7591 mL 1.5183 mL 3.7957 mL
25 mM 0.1215 mL 0.6073 mL 1.2146 mL 3.0366 mL
30 mM 0.1012 mL 0.5061 mL 1.0122 mL 2.5305 mL
40 mM 0.0759 mL 0.3796 mL 0.7591 mL 1.8979 mL
50 mM 0.0607 mL 0.3037 mL 0.6073 mL 1.5183 mL
60 mM 0.0506 mL 0.2530 mL 0.5061 mL 1.2652 mL
80 mM 0.0380 mL 0.1898 mL 0.3796 mL 0.9489 mL
100 mM 0.0304 mL 0.1518 mL 0.3037 mL 0.7591 mL
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Fluridone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluridone59756-60-4OthersABA biosynthesisAchnFARTF genesprimary alcoholsInhibitorinhibitorinhibit

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