2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Flutonidine

Flutonidine (ST-600) is a Clonidine (HY-12721) analogue that shows antihypertensive and sympatholytic effects. The initial hypertension produced by Flutonidine is due to stimulation of the peripheral α1, α2 adrenoceptors and the subsequent fall in blood pressure is due to the stimulation of central α2 adrenoceptors. Flutonidine reduces the arrhythmogenic and lethal effects of ouabain. Flutonidine is promising for research of ventricular arrhythmias caused by cardiac glycosides.

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Flutonidine Chemical Structure

Flutonidine Chemical Structure

CAS No. : 28125-87-3

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Flutonidine Related Antibodies

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Description

Flutonidine (ST-600) is a Clonidine (HY-12721) analogue that shows antihypertensive and sympatholytic effects. The initial hypertension produced by Flutonidine is due to stimulation of the peripheral α1, α2 adrenoceptors and the subsequent fall in blood pressure is due to the stimulation of central α2 adrenoceptors. Flutonidine reduces the arrhythmogenic and lethal effects of ouabain. Flutonidine is promising for research of ventricular arrhythmias caused by cardiac glycosides[1][2].

Molecular Weight

193.22

Formula

C10H12FN3
CAS No.
SMILES

FC1=CC=C(C)C(NC2=NCCN2)=C1
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Purity & Documentation
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Flutonidine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flutonidine28125-87-3ST-600ST600ST 600Adrenergic ReceptorBeta ReceptorClonidine analogueantihypertensivesympatholyticα1 adrenoceptorsα2 adrenoceptorsventricular arrhythmiasInhibitorinhibitorinhibit

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