2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Formoterol-1

Formoterol-1  (Synonyms: (±)Formoterol)

Cat. No.: HY-B0010B Purity: 99.84%
COA Handling Instructions

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Formoterol ((±)Formoterol) is an orally active β2-selective agonist. Formoterol potently relaxes the peripheral airways through stimulating the beta 2-adrenoceptors selectively as is the case in the central airways and that it significantly inhibits IgE-mediated slow reactive substance of anaphylaxis (SRS-A) release through beta-adrenoceptor stimulation.

For research use only. We do not sell to patients.

Formoterol-1 Chemical Structure

Formoterol-1 Chemical Structure

CAS No. : 73573-87-2

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5 mg USD 170 In-stock
10 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Formoterol ((±)Formoterol) is an orally active β2-selective agonist. Formoterol potently relaxes the peripheral airways through stimulating the beta 2-adrenoceptors selectively as is the case in the central airways and that it significantly inhibits IgE-mediated slow reactive substance of anaphylaxis (SRS-A) release through beta-adrenoceptor stimulation[1].

Molecular Weight

344.40

Formula

C19H24N2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=CNC1=CC([C@H](O)CN[C@@H](C)CC2=CC=C(OC)C=C2)=CC=C1O.[relative stereochemistry]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (725.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9036 mL 14.5180 mL 29.0360 mL
5 mM 0.5807 mL 2.9036 mL 5.8072 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.84%

COA (248 KB) HNMR (311 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9036 mL 14.5180 mL 29.0360 mL 72.5900 mL
5 mM 0.5807 mL 2.9036 mL 5.8072 mL 14.5180 mL
10 mM 0.2904 mL 1.4518 mL 2.9036 mL 7.2590 mL
15 mM 0.1936 mL 0.9679 mL 1.9357 mL 4.8393 mL
20 mM 0.1452 mL 0.7259 mL 1.4518 mL 3.6295 mL
25 mM 0.1161 mL 0.5807 mL 1.1614 mL 2.9036 mL
30 mM 0.0968 mL 0.4839 mL 0.9679 mL 2.4197 mL
40 mM 0.0726 mL 0.3630 mL 0.7259 mL 1.8148 mL
50 mM 0.0581 mL 0.2904 mL 0.5807 mL 1.4518 mL
60 mM 0.0484 mL 0.2420 mL 0.4839 mL 1.2098 mL
80 mM 0.0363 mL 0.1815 mL 0.3630 mL 0.9074 mL
100 mM 0.0290 mL 0.1452 mL 0.2904 mL 0.7259 mL
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Formoterol-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Formoterol-173573-87-2(±)FormoterolFormoterol1Formoterol 1Adrenergic ReceptorBeta ReceptorselectiveoralstimulationSRS-AInhibitorinhibitorinhibit

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