Formycin A (Synonyms: NSC 102811)

Cat. No.: HY-102026 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC₅₀ of 10 μM. Formycin A shows antitumor and antiviral activities.

For research use only. We do not sell to patients.

Formycin A Chemical Structure

CAS No. : 6742-12-7

Size	Price	Stock
5 mg	USD 650	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Formycin A:

Formycin A monohydrate Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All HIV Isoform Specific Products:

View All Isoforms

HIV HIV-1 HIV-2

View All Antibiotic Isoform Specific Products:

View All Isoforms

Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

HIV-1

10 μM (EC₅₀)

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	1 μM Compound: formycin A	Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr	[PMID: 4068000]
MDCK	CC₅₀	2.6 μM Compound: 7; FMA	Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay	[PMID: 35092894]

In Vitro

Formycin A (NSC 102811; 1 μM, 5 μM, 10 μM) antagonizes Zidovudine (AZT; a dideoxynucleoside chain terminator).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

267.24

Formula

C₁₀H₁₃N₅O₄

CAS No.

6742-12-7

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)C2=NNC3=C2N=CN=C3N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Dapp MJ , et al. Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1.J Virol. 2014 Jan;88(1):354-63. [Content Brief]

[2]. Zhang M, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds. Appl Environ Microbiol. 2020 Jan 7;86(2). [Content Brief]

Formycin A Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks