1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Foscarbidopa

Foscarbidopa  (Synonyms: ABBV-951; Carbidopa 4′-monophosphate)

Cat. No.: HY-109131 Purity: 95.91%
COA Handling Instructions

Foscarbidopa (ABBV-951; Carbidopa 4′-monophosphate) is a proagent of Carbidopa, acts as a dopamine receptor agonist.

For research use only. We do not sell to patients.

Foscarbidopa Chemical Structure

Foscarbidopa Chemical Structure

CAS No. : 1907685-81-7

Size Price Stock Quantity
1 mg USD 340 In-stock
5 mg USD 850 In-stock
10 mg USD 1360 In-stock
25 mg USD 2720 In-stock
50 mg USD 4400 In-stock
100 mg USD 7050 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Foscarbidopa (ABBV-951; Carbidopa 4′-monophosphate) is a proagent of Carbidopa, acts as a dopamine receptor agonist[1][2].

IC50 & Target

dopamine receptor[2]

Molecular Weight

306.21

Formula

C10H15N2O7P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OC(C=CC(C[C@@](NN)(C)C(O)=O)=C1)=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 40 mg/mL (130.63 mM; ultrasonic and warming and adjust pH to 9 with 1 M NaOH and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2657 mL 16.3287 mL 32.6573 mL
5 mM 0.6531 mL 3.2657 mL 6.5315 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.2657 mL 16.3287 mL 32.6573 mL 81.6433 mL
5 mM 0.6531 mL 3.2657 mL 6.5315 mL 16.3287 mL
10 mM 0.3266 mL 1.6329 mL 3.2657 mL 8.1643 mL
15 mM 0.2177 mL 1.0886 mL 2.1772 mL 5.4429 mL
20 mM 0.1633 mL 0.8164 mL 1.6329 mL 4.0822 mL
25 mM 0.1306 mL 0.6531 mL 1.3063 mL 3.2657 mL
30 mM 0.1089 mL 0.5443 mL 1.0886 mL 2.7214 mL
40 mM 0.0816 mL 0.4082 mL 0.8164 mL 2.0411 mL
50 mM 0.0653 mL 0.3266 mL 0.6531 mL 1.6329 mL
60 mM 0.0544 mL 0.2721 mL 0.5443 mL 1.3607 mL
80 mM 0.0408 mL 0.2041 mL 0.4082 mL 1.0205 mL
100 mM 0.0327 mL 0.1633 mL 0.3266 mL 0.8164 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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