2. GPCR/G Protein
  3. Angiotensin Receptor
  4. GA 0113

GA 0113 is a potent and orally active angiotensin II (Ang II) AT1-receptor antagonist. GA 0113 inhibits the Ang II (HY-13948)-induced pressor response with ID50 of 0.032 mg/kg and dose-dependently increases plasma renin activity for 48 h.

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GA 0113 Chemical Structure

GA 0113 Chemical Structure

CAS No. : 200639-61-8

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GA 0113 Related Antibodies

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Description

GA 0113 is a potent and orally active angiotensin II (Ang II) AT1-receptor antagonist. GA 0113 inhibits the Ang II (HY-13948)-induced pressor response with ID50 of 0.032 mg/kg and dose-dependently increases plasma renin activity for 48 h[1].

Molecular Weight

539.57

Formula

C27H24F3N5O2S
CAS No.
SMILES

O=S(NC1=C(C2=NC3=C(C=C2)C=C(CN4C5=NC(C)=CC(C)=C5N=C4CC)C=C3)C=CC=C1)(C(F)(F)F)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GA 0113 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GA 0113200639-61-8GA0113GA-0113Angiotensin ReceptorantihypertensiveAng IIorally activeplasma reninInhibitorinhibitorinhibit

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GA 0113
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HY-167886
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