2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. LXR
  4. GAC0001E5

GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research.

For research use only. We do not sell to patients.

GAC0001E5 Chemical Structure

GAC0001E5 Chemical Structure

CAS No. : 927969-67-3

Size Price Stock Quantity
5 mg USD 290 In-stock
10 mg USD 460 In-stock
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Based on 1 publication(s) in Google Scholar

GAC0001E5 Related Antibodies

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Description

GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research[1].

Molecular Weight

331.29

Formula

C17H12F3N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N=C(NC(C2=CC=CC=C2)=C1)NC3=CC=CC(C(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (377.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0185 mL 15.0925 mL 30.1850 mL
5 mM 0.6037 mL 3.0185 mL 6.0370 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0185 mL 15.0925 mL 30.1850 mL 75.4626 mL
5 mM 0.6037 mL 3.0185 mL 6.0370 mL 15.0925 mL
10 mM 0.3019 mL 1.5093 mL 3.0185 mL 7.5463 mL
15 mM 0.2012 mL 1.0062 mL 2.0123 mL 5.0308 mL
20 mM 0.1509 mL 0.7546 mL 1.5093 mL 3.7731 mL
25 mM 0.1207 mL 0.6037 mL 1.2074 mL 3.0185 mL
30 mM 0.1006 mL 0.5031 mL 1.0062 mL 2.5154 mL
40 mM 0.0755 mL 0.3773 mL 0.7546 mL 1.8866 mL
50 mM 0.0604 mL 0.3019 mL 0.6037 mL 1.5093 mL
60 mM 0.0503 mL 0.2515 mL 0.5031 mL 1.2577 mL
80 mM 0.0377 mL 0.1887 mL 0.3773 mL 0.9433 mL
100 mM 0.0302 mL 0.1509 mL 0.3019 mL 0.7546 mL
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GAC0001E5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GAC0001E5927969-67-3LXRLiver X receptorLXR inverse agonistInhibitorinhibitorinhibit

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