Gamma-Glu-Abu TFA

Cat. No.: HY-P4376A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC₅₀ of 0.21 μM in HEK-293 cell.

For research use only. We do not sell to patients.

Gamma-Glu-Abu TFA Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Gamma-Glu-Abu TFA:

Gamma-Glu-Abu Get quote

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Purity & Documentation
References
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Description

Molecular Weight

346.26

Formula

C₁₁H₁₇F₃N₂O₇

Appearance

Solid

Sequence

Gamma-Glu-Abu

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (144.40 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8880 mL	14.4400 mL	28.8800 mL
5 mM	0.5776 mL	2.8880 mL	5.7760 mL
10 mM	0.2888 mL	1.4440 mL	2.8880 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Amino Y, et al. Structure-CaSR-Activity Relation of Kokumi γ-Glutamyl Peptides. Chem Pharm Bull (Tokyo). 2016;64(8):1181-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.8880 mL	14.4400 mL	28.8800 mL	72.2001 mL
	5 mM	0.5776 mL	2.8880 mL	5.7760 mL	14.4400 mL
	10 mM	0.2888 mL	1.4440 mL	2.8880 mL	7.2200 mL
	15 mM	0.1925 mL	0.9627 mL	1.9253 mL	4.8133 mL
	20 mM	0.1444 mL	0.7220 mL	1.4440 mL	3.6100 mL
	25 mM	0.1155 mL	0.5776 mL	1.1552 mL	2.8880 mL
	30 mM	0.0963 mL	0.4813 mL	0.9627 mL	2.4067 mL
	40 mM	0.0722 mL	0.3610 mL	0.7220 mL	1.8050 mL
	50 mM	0.0578 mL	0.2888 mL	0.5776 mL	1.4440 mL
	60 mM	0.0481 mL	0.2407 mL	0.4813 mL	1.2033 mL
	80 mM	0.0361 mL	0.1805 mL	0.3610 mL	0.9025 mL
	100 mM	0.0289 mL	0.1444 mL	0.2888 mL	0.7220 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Gamma-Glu-Abu TFA Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gamma-Glu-AbuCaSRCalcium-sensing receptorHEK-293Xenopus oocytesInhibitorinhibitorinhibit

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