2. GPCR/G Protein
  3. CaSR
  4. Gamma-Glu-Abu TFA

Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC50 of 0.21 μM in HEK-293 cell.

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Gamma-Glu-Abu TFA Chemical Structure

Gamma-Glu-Abu TFA Chemical Structure

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Other Forms of Gamma-Glu-Abu TFA:

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Description

Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC50 of 0.21 μM in HEK-293 cell[1].

Molecular Weight

346.26

Formula

C11H17F3N2O7
Appearance

Solid

Color

White to light yellow

Sequence

Gamma-Glu-Abu
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (144.40 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8880 mL 14.4400 mL 28.8800 mL
5 mM 0.5776 mL 2.8880 mL 5.7760 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.8880 mL 14.4400 mL 28.8800 mL 72.2001 mL
5 mM 0.5776 mL 2.8880 mL 5.7760 mL 14.4400 mL
10 mM 0.2888 mL 1.4440 mL 2.8880 mL 7.2200 mL
15 mM 0.1925 mL 0.9627 mL 1.9253 mL 4.8133 mL
20 mM 0.1444 mL 0.7220 mL 1.4440 mL 3.6100 mL
25 mM 0.1155 mL 0.5776 mL 1.1552 mL 2.8880 mL
30 mM 0.0963 mL 0.4813 mL 0.9627 mL 2.4067 mL
40 mM 0.0722 mL 0.3610 mL 0.7220 mL 1.8050 mL
50 mM 0.0578 mL 0.2888 mL 0.5776 mL 1.4440 mL
60 mM 0.0481 mL 0.2407 mL 0.4813 mL 1.2033 mL
80 mM 0.0361 mL 0.1805 mL 0.3610 mL 0.9025 mL
100 mM 0.0289 mL 0.1444 mL 0.2888 mL 0.7220 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Gamma-Glu-Abu TFA Related Classifications

Keywords:

Gamma-Glu-AbuCaSRCalcium-sensing receptorHEK-293Xenopus oocytesInhibitorinhibitorinhibit

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