GDP-α-D-mannose disodium

Name: GDP-α-D-mannose disodium
Brand: MedChemExpress
SKU: HY-N7389B
Rating: 4.5 (1 reviews)

Cat. No.: HY-N7389B Purity: 99.76%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (K_i 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (K_i 115 μM).

For research use only. We do not sell to patients.

GDP-α-D-mannose disodium Chemical Structure

CAS No. : 148296-46-2

Size	Price	Stock	Quantity
1 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of GDP-α-D-mannose disodium:

GDP-D-mannose disodium Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]

Human Endogenous Metabolite

In Vitro

GDP-?α-D-?mannose is the alpha-anomer of GDP-D-mannose.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

649.30

Formula

C₁₆H₂₃N₅Na₂O₁₆P₂

CAS No.

148296-46-2

Appearance

Solid

Color

White to off-white

SMILES

O=P(OP(O[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(O[Na])=O)(O[Na])OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C(N=C(N)NC4=O)=C4N=C3

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (154.01 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5401 mL	7.7006 mL	15.4012 mL
5 mM	0.3080 mL	1.5401 mL	3.0802 mL
10 mM	0.1540 mL	0.7701 mL	1.5401 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.76%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (252 KB) RP-HPLC (228 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.5401 mL	7.7006 mL	15.4012 mL	38.5030 mL
	5 mM	0.3080 mL	1.5401 mL	3.0802 mL	7.7006 mL
	10 mM	0.1540 mL	0.7701 mL	1.5401 mL	3.8503 mL
	15 mM	0.1027 mL	0.5134 mL	1.0267 mL	2.5669 mL
	20 mM	0.0770 mL	0.3850 mL	0.7701 mL	1.9252 mL
	25 mM	0.0616 mL	0.3080 mL	0.6160 mL	1.5401 mL
	30 mM	0.0513 mL	0.2567 mL	0.5134 mL	1.2834 mL
	40 mM	0.0385 mL	0.1925 mL	0.3850 mL	0.9626 mL
	50 mM	0.0308 mL	0.1540 mL	0.3080 mL	0.7701 mL
	60 mM	0.0257 mL	0.1283 mL	0.2567 mL	0.6417 mL
	80 mM	0.0193 mL	0.0963 mL	0.1925 mL	0.4813 mL
	100 mM	0.0154 mL	0.0770 mL	0.1540 mL	0.3850 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.