GAGE8 - G antigen 8 Gene

Homo sapiens

Also known as CT4.8; GAGE-8

Gene ID: 100101629 | Gene type: protein coding

About GAGE8

Cytogenetic location: Xp11.4-p11.2 Genomic coordinates (GRCh38): X:37,800,001-58,100,000

Summary

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several Other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]

GAGE8 Products(1)

mRNA	Protein	Name
NM_012196.1	NP_036328.1	G antigen 2D

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

G antigen 2D

cancer/testis antigen 4.8

GAGE8 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GAGE8	Q9UEU5	FLJ13057	Homo sapiens	Q53SE7	Y2H Prey Pooling	25416956
Intra	GAGE8	Q9UEU5	FLJ13057	Homo sapiens	Q53SE7	Validated Y2H	25416956
Intra	GAGE8	Q9UEU5	FLJ13057	Homo sapiens	Q53SE7	Y2H Array	25416956
Intra	GAGE8	Q9UEU5	GMCL2	Homo sapiens	Q8NEA9	Validated Y2H	25416956
Intra	GAGE8	Q9UEU5	GMCL2	Homo sapiens	Q8NEA9	Pull Down	16189514
Intra	GAGE8	Q9UEU5	GMCL2	Homo sapiens	Q8NEA9	Y2H Prey Pooling	25416956
Intra	GAGE8	Q9UEU5	GMCL2	Homo sapiens	Q8NEA9	Y2H Pooling	16189514

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05234	GAGE8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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