FSBP - fibrinogen silencer binding protein Gene

Homo sapiens

Gene ID: 100861412 | Gene type: protein coding

About FSBP

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:94,427,716-94,436,944 (from NCBI)

This gene has 2 transcripts (splice variants) and 131 orthologues. Ubiquitous expression in testis (RPKM 1.6), prostate (RPKM 1.4) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FSBP Products(1)

mRNA	Protein	Name
NM_001256141.2	NP_001243070.1	fibrinogen silencer-binding protein

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	19060904	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	20531236	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	20531236	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FSBP Protein Structure

Myb_DNA-bind_5

0
100
200
299 a.a.

Protein Preferred Names

Protein Names

fibrinogen silencer-binding protein

FSBP Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	FSBP	O95073	FLJ13057	Homo sapiens	Q53SE7	Validated Y2H	25416956
Intra	FSBP	O95073	FLJ13057	Homo sapiens	Q53SE7	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	q9h614_human	Homo sapiens	Q9H614	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	q9h614_human	Homo sapiens	Q9H614	Y2H Array	25416956
Intra	FSBP	O95073	PRKAA1	Homo sapiens	Q13131	Validated Y2H	25416956
Intra	FSBP	O95073	ATPAF2	Homo sapiens	Q8N5M1	Y2H Array	25416956
Intra	FSBP	O95073	SUMO1	Homo sapiens	P63165	Y2H Array	25416956
Intra	FSBP	O95073	TCEANC	Homo sapiens	Q8N8B7	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	FSBP	Homo sapiens	O95073	Y2H Array	19060904
Intra	FSBP	O95073	ATPAF2	Homo sapiens	Q8N5M1	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	PRKAA1	Homo sapiens	Q13131	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	SUMO1	Homo sapiens	P63165	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	CDC23	Homo sapiens	Q9UJX2	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	FSBP	Homo sapiens	O95073	Y2H Array	25416956
Intra	FSBP	O95073	ANKRD36BP1	Homo sapiens	Q96IX9	Validated Y2H	25416956
Intra	FSBP	O95073	ENKD1	Homo sapiens	Q9H0I2	Y2H Prey Pooling	25416956
Intra	FSBP	O95073	FSBP	Homo sapiens	O95073	Y2H Pooling	19060904
Intra	FSBP	O95073	TCEANC	Homo sapiens	Q8N8B7	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Microglandular Adenosis

Breast Fibrocystic Disease	Adenosis - Breast
Adenosis Of The Breast	Fibrocystic Breast Disease
Breast Adenosis	Adenosis Of Breast

Postmenopausal Atrophic Vaginitis

Atrophic Vaginitis	Senile Vaginitis
Senile Atrophic Vaginitis	Atrophy Of Vagina
Vaginal Atrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05117	FSBP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	FSBP	MGD	MGI:5301008
Bos taurus	FSBP	VGNC	VGNC:55754
Macaca mulatta	FSBP	VGNC	VGNC:104455
Rattus norvegicus	FSBP	RGD	RGD:7611658

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