LRRC23 - leucine rich repeat containing 23 Gene

Homo sapiens

Also known as LRPB7

Gene ID: 10233 | Gene type: protein coding

About LRRC23

This gene has 15 transcripts (splice variants), 185 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.2), lung (RPKM 5.4) and 20 other tissues.

Summary

Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

LRRC23 Products(3)

mRNA	Protein	Name
NM_001135217.2	NP_001128689.1	leucine-rich repeat-containing protein 23 isoform a
NM_006992.4	NP_008923.1	leucine-rich repeat-containing protein 23 isoform b
NM_201650.3	NP_964013.1	leucine-rich repeat-containing protein 23 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in flagellated sperm motility	IMP IMP: Inferred from mutant phenotype	37804054	GOA
involved in radial spoke assembly	IMP IMP: Inferred from mutant phenotype	37804054	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in sperm flagellum	IMP IMP: Inferred from mutant phenotype	37804054	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC23 Protein Structure

LRR_1

LRR_9

0
100
200
300
343 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeat-containing protein 23

leucine-rich protein B7

LRRC23 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	LRRC23	Q53EV4	CEP55	Homo sapiens	Q53EZ4	Validated Y2H	32296183
Intra	LRRC23	Q53EV4	CEP55	Homo sapiens	Q53EZ4	Y2H Prey Pooling	32296183
Intra	LRRC23	Q53EV4	CEP55	Homo sapiens	Q53EZ4	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Renal Wilms' Tumor

Nonanaplastic Renal Wilm'S Tumor	Nonanaplastic Renal Wilm'S Tumour
Nonanaplastic Renal Wilms Tumor	Renal Wilms' Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07811	LRRC23 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LRRC23	VGNC	VGNC:57433
Mus musculus	LRRC23	MGD	MGI:1315192
Macaca mulatta	LRRC23	VGNC	VGNC:100074
Bos taurus	LRRC23	VGNC	VGNC:56220
Rattus norvegicus	LRRC23	RGD	RGD:1304779

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