2. Gene
  3. CAP1 - cyclase associated actin cytoskeleton regulatory protein 1 Gene

CAP1 - cyclase associated actin cytoskeleton regulatory protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CAP; CAP1-PEN

Gene ID: 10487 | Gene type: protein coding

About CAP1

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:40,040,240-40,072,648 (from NCBI)

This gene has 19 transcripts (splice variants), 230 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 105.5), lymph node (RPKM 89.3) and 25 other tissues.

Summary

The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]

CAP1 Products(14)

mRNA Protein Name
NM_001105530.2 NP_001099000.2 adenylyl cyclase-associated protein 1 isoform a
NM_001330502.2 NP_001317431.2 adenylyl cyclase-associated protein 1 isoform b
NM_001350475.2 NP_001337404.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350476.2 NP_001337405.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350477.3 NP_001337406.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350478.2 NP_001337407.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350479.2 NP_001337408.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350480.2 NP_001337409.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350481.2 NP_001337410.2 adenylyl cyclase-associated protein 1 isoform a
NM_001350482.2 NP_001337411.2 adenylyl cyclase-associated protein 1 isoform b
NM_001350483.2 NP_001337412.2 adenylyl cyclase-associated protein 1 isoform b
NM_001350484.2 NP_001337413.2 adenylyl cyclase-associated protein 1 isoform b
NM_001350485.2 NP_001337414.2 adenylyl cyclase-associated protein 1 isoform b
NM_006367.4 NP_006358.2 adenylyl cyclase-associated protein 1 isoform a

CAP1 Protein Structure

CAP_N

CAP_N: Adenylate cyclase associated (CAP) N terminal (4 - 305)

CAP_C

CAP_C: Adenylate cyclase associated (CAP) C terminal (317 - 473)

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  • 475 a.a.
Protein Preferred Names Protein Names

adenylyl cyclase-associated protein 1

CAP, adenylate cyclase-associated protein 1

Related Diseases

Diseases Alias
Anteroseptal Myocardial Infarction
Luminal Breast Carcinoma A

Breast Tumor Luminal

Luminal A Breast Carcinoma

Luminal Breast Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-145979 m7GpppUmpG / Unkown
HY-145980 m7GpppUpG / Unkown
HY-145981 m7GpppCpG / Unkown
HY-145982 m7GpppCmpG / Unkown
HY-D0869S 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 / Unkown
HY-E70081 mRNA Cap 2'-O-methyltransferase / Unkown
HY-RS01880 CAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CAP1 MGD MGI:88262
Rattus norvegicus CAP1 RGD RGD:620309
Felis catus CAP1 VGNC VGNC:60346
Bos taurus CAP1 VGNC VGNC:26737
Macaca mulatta CAP1 VGNC VGNC:99860
Others CAP1 NCBI